Table 2.
Outcome | Events/No. at risk | Model 1* HR (95%CI) |
P-value | Model 2† HR (95%CI) |
P-value |
---|---|---|---|---|---|
| |||||
Hospitalization for Heart Failure | |||||
Never smoker | 135/729 | Ref | - | Ref | - |
Former smoker | 225/872 | 1.44 (1.15, 1.80) | 0.0012 | 1.25 (0.99, 1.57) | 0.053 |
Current smoker | 27/116 | 1.55 (1.01, 2.38) | 0.044 | 1.68 (1.08, 2.61) | 0.020 |
| |||||
Death | |||||
Never smoker | 142/729 | Ref | - | Ref | - |
Former smoker | 202/872 | 1.10 (0.88, 1.37) | 0.42 | 1.02 (0.81, 1.29) | 0.85 |
Current smoker | 30/116 | 1.96 (1.30, 2.97) | 0.0014 | 1.82 (1.19, 2.78) | 0.0057 |
| |||||
Cardiovascular Death | |||||
Never smoker | 85/729 | Ref | - | Ref | - |
Former smoker | 113/872 | 1.03 (0.77, 1.38) | 0.85 | 1.00 (0.74, 1.35) | 0.99 |
Current smoker | 20/116 | 2.06 (1.23, 3.44) | 0.0058 | 1.85 (1.09, 3.14) | 0.022 |
Adjusted for age, sex, and race.
Adjusted for Model 1 covariates plus systolic blood pressure, serum creatinine, diabetes, chronic obstructive pulmonary disease, body mass index, aspirin, antihypertensive medications, statins, randomization group, New York Heart Association Class, coronary heart disease, and stroke.
CI=confidence interval; HR=hazard ratio.