Table 2.
Percentages of the applied topical dose absorbed following three different topical treatment periods, and all data taken together, as calculated by noncompartmental methods from (1) blood data and (2) urinary excretion data
| Treatment | A | B | C | All |
|---|---|---|---|---|
| (1) Noncompartmental methods from blood data | ||||
| Mean | 0.0198 | 0.0260 | 0.0206 | 0.0221 |
| SD | 0.0077 | 0.0185 | 0.0076 | 0.0123 |
| CV (%) | 39 | 71 | 37 | 55 |
| Min | 0.0131 | 0.0114 | 0.0131 | 0.0114 |
| Max | 0.0354 | 0.0759 | 0.0361 | 0.0759 |
| (2) Noncompartmental methods from urinary excretion data | ||||
| Mean | 0.0078 | 0.0081 | 0.0122 | 0.0094 |
| SD | 0.0064 | 0.0113 | 0.0192 | 0.0131 |
| CV (%) | 81 | 140 | 158 | 140 |
| Min | 0.0021 | 0.0022 | 0.0020 | 0.0020 |
| Max | 0.0200 | 0.0410 | 0.0625 | 0.0625 |
Mean, SD, coefficient of variation (CV %) and minimum and maximum observation among 11 subjects are given.
A = daily use of antiperspirant without shaving; B = daily use of antiperspirant and daily shaving; C = no use of daily antiperspirant without shaving.