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. 2018 Oct 30;14(10):e1007751. doi: 10.1371/journal.pgen.1007751

Fig 4. Nucleotide binding domain (NBD) regulated Hsp70 specificity against α-syn-mediated toxicity.

Fig 4

(A) Schematic representation showing the domain architecture of Ssa2, Ssa3 and hybrid Ssa Hsp70s. (B) Growth phenotypes of indicated strains on solid selective SD media upon overexpression of α-syn. Growth was monitored as described in Fig 1A. Similar to strain A3, α-syn associated toxicity was reduced in strain A32.