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. 2018 Sep 23;17(18):2230–2242. doi: 10.1080/15384101.2018.1520557

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Figure 6. — MicroRNA-378 reduced the percentage of oocyte maturation. (a) Oocytes after IVM 16–18 h. (b) Percentage of IVM after different treatments. (c) Normal and abnormal spindle assembling of oocytes. (D) The ratio of abnormal spindle assembling of oocytes after different treatments. (e) The treated female mice were maintained at normal condition and were mated with normal male mice. After birth, the average number of pups was counted. (f) The compared number of pups/litter in each batch of the paired breeding. Data are Mean ± SD of at least three independent experiments; *P < 0.05; **P < 0.01; ***P < 0.001.