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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Mol Neurobiol. 2017 Nov 11;55(7):5976–5992. doi: 10.1007/s12035-017-0816-8

Fig. 5. HIV-1 and TLR3 ligands induce transcriptional upregulation of IL6 and transcription factors associated with the TAK1 and JNK pathways in HBMEC.

Fig. 5

Quantitative real-time PCR showed that exposure of HBMEC to PIC (50 µg/ml) or HIV-1ADA (MOI: 0.001) for 2 to 24 hours induce transcriptional upregulation of IL6 (a), JUN (b), RELB (c), CEBPA (d), CEBPG (e), and STAT1 (f). *P<0.05, **P<0.01, ***P<0.001 compared to untreated controls. These are representative data from three independent experiments using HBMEC from three different human donors.