Table 1. Demographic characteristics and immunological parameters of 87 children living with HIV and 221 uninfected controls in Tororo, Uganda.
| HIV-1 Subtype | HEU group | ||||
|---|---|---|---|---|---|
| Characteristics | A N=69 (79.3%) | D N=18 (20.7%) | P-value for subtype comparison | Uninfected reference group N=221 | P-value for comparison of A, D, and reference groups |
| Age (yrs), Mean (SD) | 3.29 (0.93) | 2.76 (0.74) | <.01 | 2.87 (0.42) | <0.01 |
| Sex, N (%) | 0.08 | <0.01 | |||
| Boys | 31 (45) | 4 (22) | 125 (57) | ||
| Girls | 38 (55) | 14 (78) | 96 (43) | ||
| Wealth Group | 0.99 | 0.72 | |||
| Lowest 20% | 12 (17) | 3 (17) | 46 (21) | ||
| Middle 60% | 46 (67) | 12 (67) | 124 (58) | ||
| Upper 20% | 11 (16) | 3 (16) | 45 (21) | ||
| WAZ, Mean (SD) | -0.80 (1.65) | -0.72 (1.40) | 0.84 | -1.20 (1.12) | 0.04 |
| CD4+ %, Mean (SD) | 45.63 (13.81) | 43.47 (14.40) | 0.57 | N/A | |
| CD8+ %, Mean (SD) | 47.57 (13.88) | 45.00 (15.66) | 0.51 | N/A | |
| CD4+ lymphocyte count (copies/ml), Mean (SD) | 1439.6 (801.5) | 1362.9 (744.5) | 0.72 | N/A | |
| CD8+ lymphocyte count (copies/ml), Mean (SD) | 1544.3 (947.7) | 1270.5 (641.5) | 0.26 | N/A | |
| Log plasma HIV RNA level (copies/ml), Mean (SD) | 8.58 (2.90) | 10.01 (2.92) | 0.09 | N/A | |
| Currently on ART, N (%) | 0.49 | ||||
| No | 21 (30) | 7 (39) | N/A | ||
| Yes | 48 (70) | 11 (61) | N/A |
HEU: HIV Exposed Uninfected