Table 1.
| Dataset | Cohort | Region | Reference | Description |
|---|---|---|---|---|
| Psychiatry datasets | ||||
| GSE21138 | VBBN | DLPC (BA46) | (81) | Human bulk tissue |
| GSE53987 | ACOME | DLPC (BA46) Hippocampus Striatum |
(82) | Human bulk tissue |
| McLean | McLean66 | DLPC (BA9) | NA | Human bulk tissue |
| GSE35978 | SMRI (A+C) |
Parietal cortex, cerebellum |
(83) | Human bulk tissue |
| Study17Laeng | SMRI (A) | Hippocampus | NA | Human bulk tissue |
| Study1AltarA | SMRI (A) | DLPFC (BA46) | NA | Human bulk tissue |
| Study3Bahn | SMRI (A) | DLPFC (BA46) | (84) | Human bulk tissue |
| Study5Dobrin | SMRI (A) | DLPFC (BA46) | NA | Human bulk tissue |
| Study7Kato | SMRI (A) | DLPFC (BA46) | (21) | Human bulk tissue |
| Study16Kemether | SMRI (C) | Thalamus | NA | Human bulk tissue |
| Study2AltarC | SMRI (C) | DLPFC (BA46/BA10) |
NA | Human bulk tissue |
| Study4Chen | SMRI (C) | PFC (BA6) | NA | Human bulk tissue |
| GSE80655 | PNDRC | DLPFC | (18) | Human bulk tissue |
| PsychEncode | * | DLPFC (BA46) | NA | Human bulk tissue |
| CommonMind | * | DLPFC (BA9) | NA | Human bulk tissue |
| Development datasets | ||||
| GSE13564 | UMBB | PFC | (85) | Human bulk tissue |
| GSE25219 | DNYU | DLPFC | (86) | Human bulk tissue |
| GSE17806 | ----- | Cortical fsPV cells | (48) | Pooled mouse cells |
| Other | ||||
| GSE67835 | ----- | Cortex | (49) | Human single cell |
Datasets analyzed in the current study.
VBBN – Victorian Brain Bank Network; ACOME – Allegheny County Office of the Medical Examiner (Pittsburgh, PA); McLean66 – McLean66 coll ection, Harvard Brain Tissue Resource Center, SMRI (A) – Stanley Medical Research institute, Array collection; SMRI (C) – Stanley Medical Research institute, Consortium collection; PNDRC - Pritzker Neuropsychiatric Disorders Research Consortium; UMBB - National Child Health and Human Development Brain and Tissue Bank for Developmental Disorders at the University of Maryland; DNYU - Department of Neurobiology at Yale University School of Medicine. DLPFC – dorsolateral prefrontal cortex; PFC – prefrontal cortex. NA – un published. Reference indicates the publication that first reported the data.
Details are provided in the supplement.