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. 2018 Nov 9;8:16626. doi: 10.1038/s41598-018-34761-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Treatment effect on OTU composition. Change (%) in geometric means of relative abundance and corresponding P-values derived from linear mixed models of treatment effect i.e. alkaline versus neutral water. Prevalence indicates number of participants in which a given OTU is present in at least one sample. Abundance indicates mean relative abundance of a given OTU in baseline samples. Taxonomy of OTUs [Greengenes ID] is given at the lowest classified rank. Only OTUs with P ≤ 0.05 are annotated.