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. 2018 Nov 9;8:16638. doi: 10.1038/s41598-018-35086-z

Table 2.

Cluster analysis of ncRNAs without repetitive values of fold change.

CLUSTER piRNAs lncRNAs (Intronic) lncRNAs (Antisense) lncRNAs (Sense) lincRNAs
Totally Positive 2 4 91 31 7
Globally Positive 0 1 18 20 1
Positive in one time point only 5 3 151 74 12
Totally Negative 4 2 52 32 1
Globally Negative 0 1 33 19 4
Negative in one time point only 7 3 112 47 11
50% 0 0 52 25 7
TOTAL 18 14 509 248 43

All significant differentially expressed ncRNAs with no repetitive fold change were clustered by the presence of increased FCs in more than two times points and no fold change reduction (“totally positive”), increased FCs in a single time point (“positive in 1 time point only”) or with a prevalence of raised FCs over decreased ones (“globally positive”) throughout all analyzed time points. The same approach was, then, considered for down–regulated ncRNAs (“totally negative”, “globally negative” and “negative in 1 time point only”). A final cluster was, then, created based on a perfect balance between up–regulated and down–regulated time points (“50%”).