Table 1.
Colorectal Cancer Cell Line Panel
| Cell Line | Mutations |
|---|---|
| LoVo | KRAS heterozygous G13D |
| FBXW7 heterozygous R505C | |
| SW48 | EGFR G719S |
| FBXW7 S668fs* (Frame_Shift_Del) | |
| AKT2, FANCD2, FGFR1 | |
| HT29 | BRAF (V600E, T119S) |
| PI3CA | |
| FGFR3 | |
| RKO | BRAF |
| PI3CA | |
| BUB1 (Y259C) | |
| DNMT3B (V616M) | |
| BRAF (V600E) | |
| TGFBR2 (V561A) | |
| HSP90AA1 (D515N, N626D) | |
| Caco2 | P53 |
| LS411N | BRAF homozygous V600E |
| FBXW7 heterozygous P505H | |
| EGFR (E34*, Q478E, T940A) | |
| ErbB3, ErbB4 (P837G), DAPK (S1096N), | |
| STAT3 (T178fs), Src (V380M) | |
| HIP1, HIPK3, HDAC3, JAK2 | |
| cMET (T861) | |
| DLD1 | KRAS G13D |
| P53 | |
| PIK3CA E545K and D549N | |
| HCT116 | KRAS G13D |
| PIK3CA H1047R | |
| cMet V237fs (Frame Shift) | |
| FGFR1 and FGFR2 | |
| SW620 | KRAS G12V |
| HCT116 | KRAS G13D/+ (heterozygous) |