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. 2018 Nov 6;13:7167–7181. doi: 10.2147/IJN.S174553

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© 2018 Li et al. This work is published and licensed by Dove Medical Press Limited

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H&E staining of bone defect area at 6 weeks postsurgery.

Notes: (A, F, and K) Con group; (B, G, and L) GH implantation group; (C, H, and M) GH/A implantation group; (D, I, and N) GH/B implantation group; and (E, J, and O) GH/A/B implantation group. S: scaffold remnants; red arrows indicate the ends of GH/A/B scaffolds, which were embedded in the newly formed bone; black arrows: bone deposition line. Yellow arrows: osteocytes embedded in bone matrix. Blue arrows: inflammatory cells. Green rectangular box together with green arrow point to its enlarged image. (A–E) The same scale bar of 500 μm, (F–J) the same scale bar of 100 μm, and (K–O) the same scale bar of 25 μm.

Abbreviations: Con, control; GH, gelatin/hydroxyapatite.