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. 2018 Nov 2;24:7850–7861. doi: 10.12659/MSM.911410

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© Med Sci Monit, 2018

This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

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Effects of DHC and DOX migration and invasion of lung cancer cells. (A) Representative photomicrographs of cell migration analyzed by wound-healing assay (40×). Quantification of the number of migrated cells at 24 h of treatment is represented as the percentage of the vehicle control. DHC – dehydrocostus lactone; DOX – doxorubicin. * P<0.05 vs. control; ** P<0.05 vs. DOX or DHC. ^# P=0.041 vs. control. (B) A549 cells were treated with DOX and/or DHC and MMPs expression levels were analyzed by qPCR.