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DHC inhibits angiogenesis and enhances effects of DOX. (A) Matrigel plugs were implanted in C57BL/6 mice (n=5). (B) Masson-Trichrome staining from sections of the Matrigel plug (40×). Scale bar 100 μM. (C) Hemoglobin content was analyzed data represented as mean ±SD. DHC – dehydrocostus lactone; DOX – doxorubicin. * P<0.05 vs. control; # P<0.001 vs. control; ** P<0.038 vs. DOX; *** P<0.022 vs. DHC.
