Fig. 6.

In (a), the effective attenuation optical property map is generated and masked to include pixels at 20% the maximum Cherenkov value or greater, as shown in (b). The uncorrected CI exhibits darker regions due to near-surface vasculature, the nipple, and surgical scar. The attenuation introduced by blood absorption due to subcutaneous blood vessels yields a contrast percent difference of up to 19%, emphasized in (c). In (e), the corrected CI is adjusted, pixel-by-pixel, using the methodology discussed in Eq. (4), and magnified in (f) to again emphasize the region, where the SFDI is best in focus. To illustrate an ideal theoretical case, the 5-mm subsurface dose is read from DICOM format, aligned to the same view angle as of Cherenkov and SFD cameras, rendered in VTK, and exported from the Cherenkov imaging software (d).