Table 1.
Cohort (n = 3,767) | Low-Activity Declining (n = 1,854) | Moderate-Activity Declining (n = 2,335) | High-Activity Declining (n = 492) | p Valuea | |
---|---|---|---|---|---|
Age (years) | 79.24 ± 5.2 | 78.8 ± 5.1 | 79.4 ± 5.12 | 79.93 ± 5.72 | <.0001 |
Weight (kg) | 81.46 ± 13.4 | 83.62 ± 14.74 | 80.42 ± 12.33 | 79.11 ± 12.5 | <.0001 |
Height (cm) | 173.17 ± 6.83 | 173.58 ± 7.12 | 172.99 ± 6.69 | 172.62 ± 6.44 | .01 |
Body mass index (kg/m2) | 27.12 ± 3.91 | 27.71 ± 4.36 | 26.83 ± 3.53 | 26.51 ± 3.72 | <.0001 |
Caucasian | 3,405 (90.39) | 1,247 (89.14) | 1,766 (91.12) | 392 (91.16) | .13 |
College education | 2,125 (56.41) | 806 (57.61) | 1,082 (55.83) | 237 (55.12) | .50 |
Married | 3,197 (84.87) | 1,156 (82.63) | 1,674 (86.38) | 367 (85.35) | .01 |
Alcohol (<1 drink/wk) | 1,398 (37.11) | 562 (40.17) | 681 (35.14) | 155 (36.05) | .06 |
Alcohol (1–5 drinks/wk) | 992 (26.33) | 348 (24.87) | 526 (27.14) | 118 (27.44) | |
Alcohol (6+ drinks/wk) | 1,377 (36.55) | 489 (34.95) | 731 (37.72) | 157 (36.51) | |
Current smoking | 73 (1.94) | 26 (1.86) | 42 (2.17) | 5 (1.16) | .38 |
At least one comorbidityb | 1,524 (40.46) | 689 (49.25) | 710 (36.64) | 125 (29.07) | <.0001 |
Self-reported health status | 3,214 (85.32) | 1,086 (77.63) | 1,723 (88.91) | 405 (94.19) | <.0001 |
GDS depression (0–15) | 1.92 ± 2.21 | 2.53 ± 2.54 | 1.64 ± 1.95 | 1.2 ± 1.7 | <.0001 |
Teng 3 MMS score | 91.94 ± 7.18 | 91.28 ± 8.09 | 92.43 ± 6.43 | 91.93 ± 7.11 | .001 |
PASE score | 130.53 ± 68.72 | 78.17 ± 42.83 | 146.55 ± 50.56 | 228.68 ± 64.67 | <.0001 |
All-cause mortality | 1,435 (38.09) | 609 (43.53) | 681 (35.14) | 145 (33.72) | <.0001 |
CVD mortality | 484 (12.85) | 202 (14.44) | 235 (12.13) | 47 (10.93) | .07 |
Cancer mortality | 343 (9.11) | 136 (9.72) | 166 (8.57) | 41 (9.53) | .49 |
Non-CVD/cancer mortality | 608 (16.14) | 271 (19.37) | 280 (14.45) | 57 (13.26) | .0002 |
Notes: 3 MMS = Modified Mini-Mental State; CVD = cardiovascular disease; GDS = Geriatric Depression Scale; MrOS = Osteoporotic Fractures in Men Study; PASE = Physical Activity Scale for the Elderly.
a p Values indicate the overall difference among physical activity trajectories, calculated using chi-squared tests for categorical variables and analysis of variance for continuous variables.
bComorbidities: chronic obstructive pulmonary disease, stroke, myocardial infarction, congestive heart failure, Parkinson’s, and diabetes.