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. 2018 Nov 9;17:417. doi: 10.1186/s12936-018-2566-0

Table 5.

Mozambique blood spot elutions that demonstrate multiple cross-reacting MSP119 antibody responses

Sample Competitor added Pf MSP119 (MFI-bg) Pm MSP119 (MFI-bg) Po MSP119 (MFI-bg) PvMSP119 (MFI-bg) PfCSP (MFI-bg) GST (MFI-bg)
Mozambique 3 PBS buffer only 24,960 13,703 11,965 21,795 23,643 4
GST 19,926 6961 6418 12,687 23,442 2
Pf MSP119 40 a 237 c 53 232 23,742 1
Pm MSP119 2211 b 17 40 210 23,283 2
Po MSP119 2487 183 27 227 23,919 3
Pv MSP119 2506 232 69 40 23,882 1
Mozambique 12 PBS buffer only 24,121 13,890 9743 10,178 25,839 20
GST 22,343 6172 4284 4944 25,547 10
Pf MSP119 62 62 36 175 25,874 10
Pm MSP119 1420 22 31 156 25,062 6
Po MSP119 1488 54 31 172 25,492 7
Pv MSP119 1726 75 49 30 25,447 8

aMultiplex bead assay responses that were completely suppressed by homologous protein competition are indicated in italics cells. These responses were below the respective cut-off values

bMultiplex bead assay responses that, as a result of heterologous competition, decreased more than 30% relative to the PBS control but remained above the respective cut-off values are indicated in bold italics cells. These values indicate some level of cross-reactivity

cMultiplex bead assay responses that were completely suppressed by heterologous protein competition are indicated in underlined cells. These responses were below the respective cut-off values