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. 2018 Nov 9;15:311. doi: 10.1186/s12974-018-1348-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — No change in location of tau deposition or neuronal loss. a Tau (pS202, pT205; AT8) labeling in somatosensory cortex of wild-type (WT) and Tg4510 (TG) mice. b NeuN labeling of neuronal nuclei in the same area of cortex. c AT8 quantification of the number of neuronal somas per cubic mm by stereology. d The total number of NeuN nuclei in cortex estimated by stereology. e The total region of interest (ROI) area per cubic micron measured for these analyses. All data were analyzed by two-way ANOVA. Error bars represent ±Std. Dev. ***p < 0.001; *p < 0.05