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. 2018 Nov 10;51:45. doi: 10.1186/s40659-018-0188-1

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — miRNA-mRNA negative regulatory networks of differentially expressed genes (DEGs) and miRNAs (DEMs). Each red circle represents an up-regulated DEG and each blue rhombus represents a down-regulated DEG; red triangles represent up-regulated DEMs and blue triangles represent down-regulated DEMs. Line thicknesses represents the Pearson correlation coefficient