Table 5.

Cytotoxic activity of the isolated compounds

Cell line	Conc. (μg/mL)	% Inhibition
		β-amyrin acetate (1)	Scopoletin (4)
HepG2	20	12.1 ± 3.4	11.4 ± 2.1
	10	16.0 ± 0.3	6.5 ± 1.2
	5	20.4 ± 2.3	0.9 ± 0.1
	2.5	8.23 ± 0.7	5.9 ± 1.2
MDA-MB-231	20	−19.6 ± 1.2	8.2 ± 1.0
	10	−13.9 ± 1.2	6.0 ± 0.3
	5	−5.5 ± 1.2	10.7 ± 9.8
	2.5	7.0 ± 0.1	15.5 ± 0.3
A549	20	2.2 ± 0.5	7.9 ± 0.4
	10	9.0 ± 1.0	14.9 ± 0.4
	5	10.8 ± 0.5	14.6 ± 0.5
	2.5	0.4 ± 0.7	14.3 ± 0.7

Results are presented as cell growth inhibition percentage at concentrations of 2.5 to 20 μg/mL, mean ± SD (n = 3). Doxorubicin was used as the positive control and exerted significant cell viability inhibitory effects against HepG2 (IC₅₀ 0.49 μg/mL), MDA-MB-231 (IC₅₀ 0.68 μg/mL)