Table 1.
Subjects characteristics and between groups comparison.
| NW (n = 30) | OW&OB (n = 40) | p | |
| Age (years) | 70.3 ± 4.7 | 69.4 ± 5.4 | ns |
| Female/male (n) | 16/14 | 23/17 | ns |
| BMI (kg ∙ (m2)−1) | 23.9 ± 2.6 | 30.1 ± 2.3 | p < 0.001 |
| Sys (mmHg) | 133.1 ± 14.7 | 147.5 ± 16.2 | p = 0.001 |
| Dia (mmHg) | 76.7 ± 7.6 | 83.9 ± 10.4 | p = 0.005 |
| Medications | |||
| Statin—n (%) | 7 (23) | 10 (25) | ns |
| Diuretics—n (%) | 5 (17) | 7 (18) | ns |
| Antiacid—n (%) | 5 (17) | 6 (15) | ns |
| Physical activity | |||
| Years | 5 ± 1 | 5 ± 2 | ns |
| Min/week | 209.4 ± 82.5 | 221.7 ± 71.3 | ns |
| Days/week | 3 ± 1 | 3 ± 1 | ns |
| 6MWT (m) | 610.1 ± 68.5 | 610.0 ± 83.7 | ns |
| Inflammatory profile | |||
| IL-10 (ng/mL) | 18.9 ± 22.6 | 16.6 ± 17.2 | ns |
| IL-1ra (ng/mL) | 61.9 ± 33.6 | 52.7 ± 24.1 | ns |
| IL-1β (ng/mL) | 9.1 ± 7.2 | 7.8 ± 5.1 | ns |
| IL-8 (ng/mL) | 5.9 ± 4.4 | 7.1 ± 4.1 | ns |
∗Plus-minus values are means ± standard deviation (SD). One-way ANOVA was used to identify between-group differences for parametric variables, followed by the Holm-Sidak test. The Kruskal-Wallis one-way analysis of variance on ranks was used for nonparametric variables, followed by the Tukey test. Note: NW: normal weight; OW&OB: overweight and obese; BMI: body mass index, activity (min/week); Sys: systolic blood pressure; Dia: diastolic blood pressure; FMD: flow-mediated dilation; 6MWT: 6-minute walking test; CRP: C-reactive protein; IL: interleukin; MCP-1: monocyte chemoattractant protein-1; TNF-α: tumor necrosis factor-α; p = p value.