Table 4.

Landmark analysis at 6 months after HSCT

Clinical TMA	N	4y OS (95% CI)	4y PFS (95% CI)	4y NRM (95% CI)	4y Relapse (95% CI)
No	965	74% (71%, 77%)	66% (62%, 69%)	11% (9%, 13%)	23% (20%, 26%)
Probable	304	62% (55%, 67%)	59% (52%, 64%)	20% (15%, 25%)	22% (17%, 26%)
Definite	81	55% (44%, 66%)	56% (44%, 66%)	34% (24%, 45%)	10% (5%, 18%)
p-value
Probable vs. No TMA		<0.001	0.048	0.001	0.310
Definite vs. No TMA		<0.001	0.010	<0.001	0.009

Abbreviations: NRM, non-relapse mortality; OS, overall survival; PFS, progress-free survival.