Table 1.
Image error (mean ± standard deviation (minimum, maximum)) relative to CT attenuation correction of PET images reconstructed utilizing deepAC in various brain regions of 28 subjects and p values from paired t tests. p < 0.0024 is defined as the Bonferroni corrected significance level
| Brain regions | deepAC error (%) | deepAC absolute error (%) | p value (deepAC vs CTAC) |
|---|---|---|---|
| Frontal lobe left | − 1.04 ± 2.35 (− 6.67, 3.32) | 2.43 ± 1.57 (0.65, 6.67) | 0.18 |
| Frontal lobe right | − 1.15 ± 2.56 (− 6.61, 4.06) | 2.59 ± 1.69 (0.82, 6.62) | 0.15 |
| Temporal lobe left | − 0.79 ± 1.70 (− 4.45, 2.22) | 2.11 ± 0.94 (1.07, 4.67) | 0.18 |
| Temporal lobe right | − 0.73 ± 1.99 (− 4.77, 2.68) | 2.32 ± 0.96 (1.10, 4.88) | 0.055 |
| Parietal lobe left | − 1.70 ± 2.25 (− 5.56, 2.22) | 2.52 ± 1.63 (0.51, 5.56) | 0.01 |
| Parietal lobe right | − 1.92 ± 2.38 (− 5.60, 2.28) | 2.79 ± 1.61 (0.69, 5.60) | 0.005 |
| Occipital lobe left | − 1.78 ± 1.95 (− 6.24, 1.40) | 2.38 ± 1.43 (0.69, 6.26) | 0.01 |
| Occipital lobe right | − 1.92 ± 2.15 (− 6.12, 2.81) | 2.75 ± 1.25 (0.89, 6.12) | 0.004 |
| Cerebellum left | − 0.22 ± 1.62 (− 3.86, 2.68) | 1.70 ± 0.76 (0.67, 3.94) | 0.154 |
| Cerebellum right | − 0.27 ± 1.78 (− 3.79, 2.83) | 1.78 ± 0.85 (0.54, 3.79) | 0.146 |
| Brainstem | 0.69 ± 1.79 (− 3.20, 3.81) | 1.77 ± 0.88 (0.74, 3.81) | 0.354 |
| Caudate nucleus left | 0.37 ± 1.71 (− 3.38, 3.69) | 1.50 ± 0.85 (0.43, 3.69) | 0.613 |
| Caudate nucleus right | 0.32 ± 1.64 (− 3.47, 3.21) | 1.33 ± 0.86 (0.33, 3.47) | 0.451 |
| Putamen left | − 0.67 ± 1.58 (− 3.80, 2.31) | 1.41 ± 1.00 (0.24, 3.80) | 0.115 |
| Putamen right | − 0.74 ± 1.53 (− 3.94, 2.08) | 1.40 ± 1.02 (0.27, 3.94) | 0.009 |
| Thalamus left | − 0.07 ± 1.59 (− 3.90, 3.05) | 1.40 ± 0.88 (0.31, 3.91) | 0.172 |
| Thalamus right | 0.00 ± 1.56 (− 4.04, 3.27) | 1.34 ± 0.91 (0.20, 4.04) | 0.283 |
| Globus pallidus left | − 0.39 ± 1.51 (− 3.71, 3.11) | 1.25 ± 0.91 (0.12, 3.71) | 0.056 |
| Globus pallidus right | − 0.56 ± 1.41 (− 3.83, 2.35) | 1.24 ± 0.92 (0.29, 3.83) | 0.013 |
| Cingulate region left | − 0.50 ± 1.68 (− 4.02, 2.70) | 1.61 ± 0.95 (0.35 4.02) | 0.049 |
| Cingulate region right | − 0.45 ± 1.63 (− 3.81, 2.28) | 1.58 ± 0.87 (0.35, 3.81) | 0.057 |
| All regions | − 0.64 ± 1.99 (− 4.18, 2.22) | 1.74 ± 0.94 (0.29, 4.20) |