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. 2018 Nov 5;9:1530. doi: 10.3389/fphys.2018.01530

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Copyright © 2018 Turco, Cazzagon, Franceschet, Formentin, Frighetto, Giordani, Cellini, Mazzotta, Costa, Middleton, Skene, Floreani and Montagnese.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pittsburgh Sleep Quality Index (PSQI) Global Score (A) and Component 7 (Dysfunction due to sleepiness; (B) before (white columns) and after 2 weeks of light administration (gray columns), by patient category (HV, healthy volunteers; PBC, Primary Biliary Cholangitis). (A) Patient category: p = 0.007; treatment: p < 0.001; patient category × treatment: p = 0.120; ^∧post-hoc significant for PBC: p < 0.001. (B) Patient category: p = 0.010; treatment: p = 0.011; patient category × treatment: p = 0.280; ^∧post-hoc significant for PBC: p = 0.021.