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. 2018 Nov 5;9:1545. doi: 10.3389/fphys.2018.01545

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Copyright © 2018 Farré, Jorba, Torres, Falcones, Martí-Almor, Farré, Almendros and Navajas.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Examples of stress–stretch curves in native (Nat) and decellularized (Dec) left ventricular myocardium tissue samples from one ovariectomized mouse (OVX; black dotted line) and from one intact mouse (SHAM; black solid line). Red solid and dashed lines correspond to exponential fits to the OVX and SHAM stress-stretch curves, respectively. (B) Passive Young’s modulus (E) of native left ventricular myocardium tissue computed at stretch λ = 1.2 in ovariectomized (OVX) and intact (SHAM) mice. (C) same as (B) in decellularized tissue (N = 8).