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. 2018 Nov 5;9:2526. doi: 10.3389/fimmu.2018.02526

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Copyright © 2018 Massari, Bellini, Ciccarese and Antonacci.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Dot-plot of the pig TRB locus sequence against itself. (A) With the exception of the main diagonal, the dots and diagonal lines indicate internal homology units in the sequence. The red boxes show the two TRBV regions underwent to duplication events and the internal homology of the D-J-C cluster portion. The gray arrow points to the homology region enlarged in (B). (B) The pattern of parallel lines indicates the duplicated region of about 28 kb containing the TRBV2 and TRBV4 genes.