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. 2018 Nov 5;9:2059. doi: 10.3389/fimmu.2018.02059

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Copyright © 2018 Sallis, Acar, Hawthorne, Babcock, Kanagaratham, Goldsmith, Rosen, Vanderhoof, Nurko and Fiebiger.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Measures of EoE severity.(A) Representative hematoxylin and eosin staining of distal esophageal biopsies of Control, EoE no FI, and EoE+FI patients. Comparison of eosinophil counts in (B) proximal and (C) distal esophageal biopsies. (D) Maximum eosinophil infiltration. (E) CCL2 mRNA transcript levels in the esophagus. (F,G) disease probability scores (p(EoE), p(Control), p(GERD)) in Control, EoE no FI, and EoE+FI patients. ^****p < 0.0001 as calculated by Dunn's multiple comparison test after Kruskal-Wallis test.