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. 2018 Nov 5;9:2059. doi: 10.3389/fimmu.2018.02059

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Copyright © 2018 Sallis, Acar, Hawthorne, Babcock, Kanagaratham, Goldsmith, Rosen, Vanderhoof, Nurko and Fiebiger.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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FI-score in EoE no FI and EoE+FI patients. (A) Transcript weights of the factors differentiating EoE and EoE+FI. (B) Volcano plots of normalized mRNA transcripts displayed as fold difference (x-axis) and significance (y-axis) used for the calculation of the factor weights. (C) Calculated standardized FI-score. (D) ROC analysis for differentiating EoE no FI and EoE+FI patients based on FI-score (AUC = 0.99, Sensitivity = 0.93 Specificity = 1).