Table 1.

Patient characteristics and cohort composition.

Parameter	EoE+FI	EoE no FI	Controls	P-values
				EoE-FI vs. EoE no FI	EoE-FI vs. Controls	EoE no FI vs. Controls
n	14	13	18
Age at diagnosis (in years; median, range)	14.26 (10.70–17.58)	13.41 (9.08–15.72)	13.39 (10.63–17.98)	0.528	>0.999	0.466
Male gender	13/14 (93%)	8/13 (62%)	6/18 (33%)	0.077	< 0.001	0.157
SYMPTOMS IN THE PAST YEAR
Dysphagia	14/14 (100%)	9/13 (69%)	5/18 (28%)	0.041	< 0.001	0.033
Food impaction	14/14 (100%)	0/13 (0%)	0/18 (0%)	NA	NA	>0.999
Chest pain	3/14 (21%)	0/13 (0%)	2/18 (11%)	0.222	0.631	0.497
Epigastric pain	4/14 (29%)	6/13(46%)	9/18 (50%)	0.440	0.289	>0.999
Reflux symptoms	4/14 (29%)	6/13(46%)	11/18 (61%)	0.440	0.087	0.481
Feeding difficulties	0/14 (0%)	0/13 (0%)	0/18 (0%)	1.000	>0.999	>0.999
Vomiting	2/14 (14%)	4/13 (31%)	2/18 (11%)	0.385	>0.999	0.208
ENDOSCOPY
Pallor	3/14 (21%)	1/13 (8%)	1/18 (6%)	0.596	0.295	>0.999
Edema	1/14 (7%)	0/13 (0%)	0/18 (0%)	>0.999	0.438	>0.999
Loss of vascularity	7/14 (50%)	2/13 (15%)	0/18 (0%)	0.103	0.001	0.168
Furrowing	11/14 (79%)	9/13 (69%)	3/18 (17%)	0.678	< 0.001	0.008
Exudate	6/14 (43%)	5/13 (38%)	0/18 (0%)	>0.999	0.003	0.008
ALLERGIC/ATOPIC CONDITIONS
Serum IgE levels (median, range)	214 (63–503)	100.5 (4–1920)	98 (35–189)	0.733	0.519	>0.999
Eczema	5/14 (36%)	3/13 (23%)	1/18 (6%)	0.678	0.064	0.284
Asthma	8/14 (57%)	5/13 (38%)	1/18 (6%)	0.449	0.004	0.059
Allergic rhinoconjunctivitis	7/14 (50%)	9/13 (69%)	4/18 (22%)	0.440	0.142	0.013
Food allergy	4/14 (29%)	3/13 (23%)	0/18 (0%)	>0.999	0.028	0.064
Positive RAST or skin prick test against food antigens	11/14 (78%)	8/13 (61%)	0/5 (0%)	0.420	0.005	0.036
TISSUE EOSINOPHILIA (PEAK VALUE)
Proximal (median, range)	25 (0–110)	25 (0–100)	0	>0.999	< 0.001	< 0.001
Distal (median, range)	50 (3–80)	70 (25–150)	0	>0.999	< 0.001	< 0.001
Maximum eosinophil count (median, range)	89 (0–115)	70 (25–150)	0	>0.999	< 0.001	< 0.001

p-values calculated by Fisher's exact test.