Table 5.

GSEA of proteins that increased in skeletal muscle mitochondrial fractions from mice fed the HFD compared with mice fed the LFD for 12 wk

GSEA Identification	Pathway	No. of Genes	FDR
R-MMU-556833	Metabolism of lipids and lipoproteins	32	5.65e-12
R-MMU-1430728	Metabolism	45	3.93e-09
R-MMU-535734	Fatty acid, triacylglycerol, and ketone body metabolism	14	2.82e-08
R-MMU-77289	Mitochondrial fatty acid β-oxidation	6	1.04e-05
R-MMU-390918	Peroxisomal lipid metabolism	6	1.33e-04
R-MMU-77286	Mitochondrial fatty acid β-oxidation of saturated fatty acids	4	1.85e-04
R-MMU-77346	β-Oxidation of decanoyl-CoA to octanoyl-CoA-CoA	3	1.93e-03
R-MMU-77348	β-Oxidation of octanoyl-CoA to hexanoyl-CoA	3	1.93e-03
R-MMU-174800	Chylomicron-mediated lipid transport	4	1.64e-02
R-MMU-6809371	Formation of the cornified envelope	6	1.64e-02

GSEA, gene set enrichment analysis; HFD, high-fat diet; LFD, low-fat diet; FDR, false discovery rate.