Table 1.
WT | ASIC3 KO | |
---|---|---|
Number of cells | 8 | 19 |
Cm, pF | 34 ± 5 | 34 ± 3 |
RMP, mV | −55 ± 3 | −59 ± 2 |
Rheobase, nA | 1.3 ± 0.3 | 1.0 ± 0.2 |
AP threshold, mV | −33 ± 2 | −31 ± 1 |
AP duration, ms | 3.2 ± 0.4 | 2.9 ± 0.1 |
Peak amplitude, mV | 111 ± 6 | 112 ± 6 |
AHP mag, mV | −10 ± 4 | −8 ± 2 |
Values are means ± SE. Cm, membrane capacitance; RMP, resting membrane potential; AP, action potential; AHP mag, magnitude of after hyperpolarization below resting membrane potential.