Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Aug 6;99(9):1187–1198. doi: 10.1099/jgv.0.001128

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 The Authors

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Fig. 1. — Scheme of recombinant viruses. The structure of recombinant viruses with name, origin of segment 4 (HA), origin of the loop, backbone segments (Other proteins) and relevant HA amino acid sequences are illustrated. Differences at the amino acid level are shown for the N-terminal part (amino acids 16–32) and the protease recognition site with its neighbouring region (amino acids 320–329, H3 numbering), which we refer to here as the ‘HA-loop’ (highlighted in green). HA₁ is highlighted in orange (except the HA-loop) and HA₂ in yellow. Differences in amino acid sequences between HA-HK and HA-PR8 are labelled red. The arrow indicates where cleavage occurs. PR8: A/Puerto Rico/8/34 (H1N1); HK: A/Hong Kong/01/68 (H3N2).