Table 1. Patient demographics, clinicopathological findings and operative outcomes.
| Characters | Median [range] or number (%), N=506 |
|---|---|
| Age | 57 [21–85] |
| Male gender | 432 (85.4) |
| Child’s grading | |
| A | 489 (96.6) |
| B | 16 (3.2) |
| C | 1 (0.2) |
| Hepatitis B carrier | 418 (82.6) |
| Hepatitis C carrier | 30 (5.9) |
| Pre-operative AFP (µg/L) | 40 [1–258,000] |
| Pre-operative TACE | 47 (9.3) |
| Pre-operative PVE | 25 (4.9) |
| Number of tumour | |
| Solitary | 382 (75.5) |
| Multinodular | 124 (24.5) |
| 2 | 56 (11.1) |
| 3 | 17 (3.4) |
| 4 | 9 (1.8) |
| ≥5 | 42 (8.3) |
| Size of largest tumour (cm) | 4 [0.7–24.0] |
| Recurrent tumour (after previous treatment except hepatectomy) | 16 (3.2) |
| Ruptured tumour | 34 (6.7) |
| Degree of differentiation | |
| Well | 62 (12.3) |
| Moderate | 390 (77.1) |
| Poor | 45 (8.9) |
| Not available | 9 (1.8) |
| Satellite nodules | 58 (11.5) |
| Macrovascular invasion | 37 (7.3) |
| Microvascular invasion | 98 (19.4) |
| Resection margin (cm) | 1.3 [0–6.5] |
| Involved margin | 14 (2.8) |
| Cirrhosis | 289 (57.1) |
| Major hepatectomy | 211 (41.7) |
| Concomitant RFA or MWA | 13 (2.6) |
| Surgical approach | |
| Open | 426 (84.2) |
| Laparoscopic | 41 (8.1) |
| Robotic | 39 (7.7) |
| 90-day mortality | 7 (1.4) |
| Morbidity | 142 (28.1) |
| Blood loss (mL) | 350 [5–11,300] |
| Blood transfusion | 44 (8.7) |
| Postoperative hospital stay (days) | 7 [2–55] |
| Adjuvant TACE | 81 (16.0) |
AFP, alpha-feto protein; TACE, transarterial chemoembolization; PVE, portal vein embolization; RFA, radiofrequency ablation; MWA, microwave ablation.