Table 2.
Differentially expressed miRNAs in the left ventricle of NHE1 transgenic mouse hearts
| Seq |
qPCR |
|||||||
|---|---|---|---|---|---|---|---|---|
| miRNA Name | RPKM (Control) | RPKM (NHE1ox) | Fold Change | P Value | Corrected P Value (Bonferroni) | Fold Change | P Value | |
| mmu-miR-208b-3p | 2241.66 | 23190.52 | 10.35 | 0.00E +00 | 0.00E +00 | 9.24 | 0.0004 | * |
| mmu-miR-206-3p | 9.49 | 61.22 | 6.45 | 0.00E +00 | 0.00E +00 | 23.75 | 0.0007 | * |
| mmu-miR-21a-5p | 18566.08 | 71506.61 | 3.85 | 0.00E +00 | 0.00E +00 | 2.64 | 0.0393 | * |
| mmu-miR-214-5p | 7.00 | 22.52 | 3.21 | 1.10E-12 | 1.29E-09 | |||
| mmu-miR-125b-1-3p | 7.68 | 24.06 | 3.13 | 4.52E-13 | 5.28E-10 | |||
| mmu-miR-21-a-3p | 22.59 | 68.68 | 3.04 | 0.00E +00 | 0.00E +00 | |||
| mmu-miR-146b-5p | 464.06 | 1267.98 | 2.73 | 0.00E +00 | 0.00E +00 | |||
| mmu-miR-379-5p | 140.53 | 371.39 | 2.64 | 0.00E +00 | 0.00E +00 | |||
| mmu-miR-199a-5p | 235.42 | 599.51 | 2.55 | 0.00E +00 | 0.00E +00 | 2.25 | 0.0569 | |
| mmu-miR-34c-5p | 98.28 | 247.26 | 2.52 | 0.00E +00 | 0.00E +00 | |||
| mmu-miR-30c-5p | 1578.11 | 539.98 | −2.92 | 0.00E +00 | 0.00E +00 | −1.43 | 0.0001 | * |
| mmu-let-7d-3p | 64.16 | 21.95 | −2.92 | 0.00E +00 | 0.00E +00 | −1.67 | 0.3922 | |
| mmu-miR-9-3p | 89.47 | 28.85 | −3.1 | 0.00E +00 | 0.00E +00 | |||
| mmu-miR-208a-3p | 13986.97 | 3826.18 | −3.66 | 0.00E +00 | 0.00E +00 | −4.00 | 0.1649 | |
| mmu-miR-499-3p | 36.60 | 9.01 | −4.06 | 0.00E +00 | 0.00E +00 | |||
miRNA (also miR), microRNA; RPKM, reads per kilobase million; qPCR, quantitative real-time PCR.
*
P < 0.05.