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. 2018 Nov;43(6):633–644.

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Copyright: © Iranian Journal of Medical Sciences

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Micrographs show the histological sections of the defects treated with PRP (A), HA/ZrO₂ (B), and HA/ZrO₂/PRP (C) at the second week. In the PRP-treated defects, just an island of osteoid and also newly differentiated osteoblasts in the form of cell condensations (a) are present. Ossified zone with bone extracellular matrix is present in both HA/ZrO₂/PRP and HA/ZrO₂-treated defects. The black area indicates the remnant of the scaffold including ZrO₂. Scale bar is 200 µm for A, B, and C and 30 µm for a.