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. 2018 Nov 2;12:788. doi: 10.3389/fnins.2018.00788

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Copyright © 2018 Pais-Roldán, Biswal, Scheffler and Yu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of the rate of artificial ventilation on the fMRI time-course. (A) The graphs show 300 s of fMRI time course from 8 different voxels, extracted from a 3D EPI in an animal ventilated at 59 bpm (0.96 Hz) (TR = 1 s). Numbers indicate the location of the voxels (see C). (^∗) indicates a phantom voxel (registration is not perfect due to misalignment between the anatomical and functional scan). (B) The map shows the distribution of the power of frequencies in the range 0.005–0.4 Hz. (C) fMRI time courses acquired with TR = 1s in a non-paralyzed animal ventilated at seven different rates.