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Relative change in levels of anti‐citrullinated protein antibodies (ACPA) immunoglobulin (Ig)G, IgM and secretory IgA (SIgA) in early rheumatoid arthritis (RA) compared with relative change in ACPA IgG levels (****represent P < 0·0001 and *P < 0·05, Kruskal–Wallis test followed by Dunn’s multiple comparisons test).
