Table 4.

Spearman correlation analysis of relative change in antibody levels during the first 3 months in relation to change in DAS28 components and VAS pain in recent‐onset RA patients at inclusion positive for the respective antibody

ACPA isotype	Swollen joints		Tender joints		CRP		ESR		Patient’s global assessment		VAS pain
	Rho	P	Rho	P	Rho	P	Rho	P	Rho	P	Rho	P
SIgA	0.355	0.001	0.426	0.001	0.304	0.006	0.356	0.001	0.228	0.043	0.322	0.004
IgM	0.344	0.002	0.488	0.001	0.395	0.001	0.387	0.001	0.228	0.049	0.266	0.020
IgG	0.201	0.010	0.200	0.010	0.105	0.185	0.093	0.243	0.148	0.062	0.197	0.013
IgA	0.243	0.009	0.130	0.165	0.265	0.005	0.175	0.068	0.223	0.019	0.132	0.168

DAS28 = disease activity score 28; ACPA = anti‐citrullinated protein antibodies; VAS = visual analogue scale; RA = rheumatoid arthritis, Ig = immunoglobulin; SIgA = secretory IgA; CRP = C‐reactive protein; ESR = erythrocyte sedimentation rate.

Bold values display statistically significant differences.