Table 1.
Demographic and clinical characteristics of the study subjects
| HC (n = 13) | CP (n = 15) | AP (n = 15) | anova P‐valuea | ||
|---|---|---|---|---|---|
| Age, mean years (range) | 36·8 (20–63) | 42·1 (36–58)# | 30·5 (19–36)# | P < 0·001 | |
| Gender | Male, n (%) | 6 (46) | 7 (47) | 8 (53) | n.s. |
| Female, n (%) | 7 (54) | 8 (53) | 7 (47) | n.s. | |
| Number of teeth, mean | 28·7 | 28·1 | 28·7 | n.s. | |
| PPD, mean ± s.d. mm | 1·73 ± 0·24 | 3·53 ± 0·69*** | 3·19 ± 0·78*** | P < 0·0001 | |
| BOP, mean ± s.d. % | 10·9 ± 7·0 | 32·1 ± 14·9* | 34·2 ± 30·9** | P < 0·01 | |
| % sites of PPD > 5 mm | 0 ± 0 | 29·5 ± 12·8*** | 23·4 ± 16·6*** | P < 0·0001 | |
| PISA, median (IQR) mm2 | 91 (42–136) | 643 (337–906)*** | 255 (137–1336)*** | P < 0·0001 | |
AP = aggressive periodontitis patients; BOP = bleeding on probing; CP = chronic periodontitis patients; GI = gingivitis patients; HC = periodontally healthy controls; PISA = periodontal inflamed surface area; PPD = probing pocket depth. Data were tested for normality using D’Agostino and Pearson omnibus normality testing and where not normally distributed data were log10‐transformed prior to analysis. Data were analysed by one‐way analysis of variance (anova) and the overall P‐value shown as a. Individual groups were compared to healthy control (HC) values by Bonferroni’s multiple comparison test for parametric data, and significant differences indicated as *P < 0·05; **P < 0·01; ***P < 0·001. Significant differences between CP and AP groups are indicated as # P < 0·05; n.s. = not significant.