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. 2018 Sep 18;62(9):1047–1063. doi: 10.1093/annweh/wxy080

Table 4.

Reliability of other assessment methods in estimating past occupational exposures in case–control studies in the population.

Authors, year Exposure Assessment method Comparison method Reliability test Results
Pronk et al., 2012 Diesel engine exhaust Use of expert-derived algorithms to assess exposure probability, intensity, and frequency based on occupational histories with specific task information Case-by-case assessment by an occupational hygienist Weighted κ for ordinal exposure measures; Spearman correlation for continuous exposure measures Weighted κ = 0.68– 0.81 for ordinal exposure probability, frequency, and intensity; Spearman ρ = 0.70– 0.72 for continuous exposure frequency and intensity
Bourgkard et al., 2013 Asbestos and PAHs Algorithmic assessment based on task-based questionnaire data Reference case-by- case assessment by two experts by consensus based on full interview data; population-based asbestos JEM (Févotte et al., 2011) Weighted κ for ordinal exposure levels; OR for lung cancer and asbestos exposure κ = 0.61 for asbestos and 0.36 for PAHs against referent expert assessment; κ = 0.26 against asbestos JEM; lung cancer OR = 1.18 (95% CI 1.06–1.31) based on algorithm- derived exposures and 1.02 (95% CI 0.91– 1.16) based on JEM- assessed exposures
Friesen et al., 2013 Diesel engine exhaust Algorithm-based assessment (Pronk et al., 2012) to assess exposure probability, intensity, and frequency based on questionnaire responses Case-by-case assessment by three experts individually and by aggregate Weighted κ for exposure probability, intensity, and frequency κ = 0.58–0.81 (median = 0.70) between individual expert rating and algorithmic assessment; κ = 0.82 for aggregated expert assessment versus algorithmic assessment
Wheeler et al., 2013 Diesel engine exhaust Use of tree-based statistical learning models to predict exposure probability, frequency, and intensity using previous expert assessments as training data Case-by-case assessment by an occupational hygienist Percent agreement for presence of exposure, and ordinal exposure probability, frequency, and intensity Percent agreement = 92–94 for presence of exposure; percent agreement = 7–90 for ordinal exposure probability, frequency, and intensity
Peters et al., 2014 Diesel engine exhaust, pesticides, and solvents Expert-derived algorithms were used to assess presence/ absence of exposure from information obtained from questionnaires Case-by-case assessment by an occupational hygienist κ agreement on presence of exposure κ = 0.51–0.84 (median 0.73)
Friesen et al., 2014 TCE A systematic process was developed to extract free-text responses in occupational histories by identifying keywords and phrases associated with exposure Case-by-case expert assessment Percent agreement on presence of exposure Percent agreement = 98.7
Friesen et al., 2015b Diesel engine exhaust Hierarchical clustering model grouped jobs with similar exposures based on questionnaire responses Algorithmic assessment of exposure probability, intensity, and frequency (Pronk et al., 2012) ICCs within job title clusters ICC > 80% for exposure probability with >500 clusters w in model; ICC > 70% for exposure frequency and intensity with > 200 model clusters
Wheeler et al., 2015 Diesel engine exhaust Use of ordinal and nominal classification tree models to predict exposure probability, frequency, and intensity using expert assessment information Case-by-case assessment by an occupational hygienist Somer’s d for nominal and ordinal exposure metrics (probability, frequency, and intensity) Somer’s d = 0.61–0.66
Friesen et al., 2016b Diesel engine exhaust Application of classification tree models (Wheeler et al., 2013) Case-by-case assessment by two experts independently Weighted κ for ordinal measures of exposure probability, intensity, and frequency Weighted κ = 0.09– 0.91; model performance was better for unexposed and highly exposed jobs, and for predicting exposure probability and intensity

CI = confidence interval; ICC = intraclass correlation coefficient; OR = odds ratio; TCE = trichloroethylene.