Table 4.
Reliability of other assessment methods in estimating past occupational exposures in case–control studies in the population.
Authors, year | Exposure | Assessment method | Comparison method | Reliability test | Results |
---|---|---|---|---|---|
Pronk et al., 2012 | Diesel engine exhaust | Use of expert-derived algorithms to assess exposure probability, intensity, and frequency based on occupational histories with specific task information | Case-by-case assessment by an occupational hygienist | Weighted κ for ordinal exposure measures; Spearman correlation for continuous exposure measures | Weighted κ = 0.68– 0.81 for ordinal exposure probability, frequency, and intensity; Spearman ρ = 0.70– 0.72 for continuous exposure frequency and intensity |
Bourgkard et al., 2013 | Asbestos and PAHs | Algorithmic assessment based on task-based questionnaire data | Reference case-by- case assessment by two experts by consensus based on full interview data; population-based asbestos JEM (Févotte et al., 2011) | Weighted κ for ordinal exposure levels; OR for lung cancer and asbestos exposure | κ = 0.61 for asbestos and 0.36 for PAHs against referent expert assessment; κ = 0.26 against asbestos JEM; lung cancer OR = 1.18 (95% CI 1.06–1.31) based on algorithm- derived exposures and 1.02 (95% CI 0.91– 1.16) based on JEM- assessed exposures |
Friesen et al., 2013 | Diesel engine exhaust | Algorithm-based assessment (Pronk et al., 2012) to assess exposure probability, intensity, and frequency based on questionnaire responses | Case-by-case assessment by three experts individually and by aggregate | Weighted κ for exposure probability, intensity, and frequency | κ = 0.58–0.81 (median = 0.70) between individual expert rating and algorithmic assessment; κ = 0.82 for aggregated expert assessment versus algorithmic assessment |
Wheeler et al., 2013 | Diesel engine exhaust | Use of tree-based statistical learning models to predict exposure probability, frequency, and intensity using previous expert assessments as training data | Case-by-case assessment by an occupational hygienist | Percent agreement for presence of exposure, and ordinal exposure probability, frequency, and intensity | Percent agreement = 92–94 for presence of exposure; percent agreement = 7–90 for ordinal exposure probability, frequency, and intensity |
Peters et al., 2014 | Diesel engine exhaust, pesticides, and solvents | Expert-derived algorithms were used to assess presence/ absence of exposure from information obtained from questionnaires | Case-by-case assessment by an occupational hygienist | κ agreement on presence of exposure | κ = 0.51–0.84 (median 0.73) |
Friesen et al., 2014 | TCE | A systematic process was developed to extract free-text responses in occupational histories by identifying keywords and phrases associated with exposure | Case-by-case expert assessment | Percent agreement on presence of exposure | Percent agreement = 98.7 |
Friesen et al., 2015b | Diesel engine exhaust | Hierarchical clustering model grouped jobs with similar exposures based on questionnaire responses | Algorithmic assessment of exposure probability, intensity, and frequency (Pronk et al., 2012) | ICCs within job title clusters | ICC > 80% for exposure probability with >500 clusters w in model; ICC > 70% for exposure frequency and intensity with > 200 model clusters |
Wheeler et al., 2015 | Diesel engine exhaust | Use of ordinal and nominal classification tree models to predict exposure probability, frequency, and intensity using expert assessment information | Case-by-case assessment by an occupational hygienist | Somer’s d for nominal and ordinal exposure metrics (probability, frequency, and intensity) | Somer’s d = 0.61–0.66 |
Friesen et al., 2016b | Diesel engine exhaust | Application of classification tree models (Wheeler et al., 2013) | Case-by-case assessment by two experts independently | Weighted κ for ordinal measures of exposure probability, intensity, and frequency | Weighted κ = 0.09– 0.91; model performance was better for unexposed and highly exposed jobs, and for predicting exposure probability and intensity |
CI = confidence interval; ICC = intraclass correlation coefficient; OR = odds ratio; TCE = trichloroethylene.