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. 2018 Oct 24;9:229–243. doi: 10.1016/j.isci.2018.10.022

Figure 6.

Figure 6

Intestinal Ssk Reduces Bacterial Translocation upon Oral Infection with Pathogenic Bacteria

(A) Survival curves of 5966GS > UAS-ssk females with or without RU486-mediated transgene induction from day 3 until day 20; then Db11 bacteria were fed to the flies and survival plotted. p < .0001, log rank test; n > 216 flies/condition.

(B) S. marcescens Db11 colony-forming units (CFUs) from dissected midguts of 5966GS > UAS-ssk females with or without RU486-mediated transgene induction from day 3 until day 20. There is no significant difference; one-way ANOVA/Tukey's multiple comparisons test. Error bars depict mean ± SEM.

(C) S. marcescens Db11 CFUs from the hemolymph of 5966GS > UAS-ssk females with or without RU486-mediated transgene induction from day 3 until day 20. There is significantly less bacteria in the hemolymph when Ssk is up-regulated. ***p < .0001; one-way ANOVA/Tukey's multiple comparisons test. Error bars depict mean ± SEM.

See also Figure S6.