Table 3. IC50 Values of 20 and 30–34 against the Growth of Colorectal Cancer Cell Lines.

From SRB assay after 72 h of treatment.
X is methyl group except compound 29 (X = H), Y is CN group except 34 (Y = H).
IC50 data are an average of at least three independent experiments.
The selectivity indexes (SI) are calculated by IC50 values in HAF divided by IC50 values in cancer cell lines.
