Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Reagents and conditions: (a) K3PO4, Pd2(dba)3, dioxane, 100 °C, 88%; (b) HCl, dioxane, EtOAc, RT, 95%; (c) Cs2CO3, DMF, RT, 86%; (d) LiOH, MeOH, 50 °C, 79%. For synthesis of intermediate 14, see Supporting Information.
