Figure 1.
IL-1β is induced in lungs after intratracheal B. abortus infection. C57BL/6 mice were intratracheally infected with 106 CFU/mouse of B. abortus in 20 μl of PBS. Mice (n = 5 per time point) were sacrificed before infection or at 3 and 7 days post-infection (0, 3, and 7d, respectively), and IL-1β was quantified in BALF (gray bars) and lung homogenates (white bars) of individual mice. Values are means ± SD of three independent experiments (*p < 0.05, **p < 0.01 vs. basal levels, ANOVA followed by Dunnett's test).