Figure 2.
Consequence of SD, SICD and necrosis. In nonrenewable cell types, SD, SICD or necrosis may cause hypertrophy of the remaining cells to restore the cell-death-caused functional loss. In renewable cell types, SD, SICD or necrosis triggers regeneration that usually results in over regeneration and ensuing apoptosis of the over-regenerated cells, which is a one-way procedure because apoptosis will not trigger regeneration.