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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: J Thromb Haemost. 2018 May 20;16(6):1164–1175. doi: 10.1111/jth.14127

Figure 2. Different warfarin sensitivity of VKORL1 and VKORC1 is not owing to their redox-state change.

Figure 2.

(A) Warfarin inhibition curves of VKORL1 and VKORC1. (B) Cellular redox status of conserved cysteines in VKORL1 (left) and VKORC1 (right), analyzed by MS-based footprinting before and after DTT reduction. Calculation of the error bars is described in Materials and Methods.