Figure 4.
Anticancer activity of peptide 7. (a) Live-cell confocal microscopic image of A2780 ovarian cancer cells after 2 h treatment with 5 μM FITC-peptide 7. I, FITC fluorescence; II, DIC. (b) Viability of ovarian cancer cells (A2780 and CP70) and noncancerous ovarian cells (OSE) in the presence of increasing concentrations of peptide 7, as determined by the methylene blue assay. (c) Comparison of peptide 7 and control peptides for their effect on the viability of A2780 cells. (d) Effect of peptide 7 and control peptides on noncancerous OSE cells. Viability tests in panel (c) and (d) were performed by the MTT assay.
