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. 2018 Nov 12;19:194. doi: 10.1186/s13059-018-1567-1

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Heatmap of m values for fetal brain cis-eQTL (FDR < 0.05) for 974 eGenes across 48 adult tissues assayed by the GTEx Consortium [4]. m values are derived from a Meta-Tissue [68] analysis performed by the GTEx consortium (using v7 data), and estimate the posterior probability that an eQTL is shared between each tissue. GTEx m values are available for 974 gene fetal brain cis-eQTL that are predicted to be shared by at least two adult tissues (m values > 0.9); the five fetal brain cis-eQTL that are eQTL in only one adult tissue (FDR < 0.05) are not included. Greatest sharing of fetal brain eQTL is observed for adult brain regions, where, on average, 79% of the tested fetal brain eQTL are predicted to be shared