Table 1.
Variables | Theoretical impact on the vessel |
---|---|
Static pressure | Associated with the proliferation of vascular smooth muscle cells |
Dynamic pressure | Associated with a variation of the blood flow velocity, which has been linked to a higher risk of re-stenosis |
Reynolds number (Re) | High Re number indicates a disturbed blood flow and is associated with a hemodynamic turbulence, which causes endothelial dysfunction and thrombogenicity. |
Vorticity magnitude | High in the presence of a severe stenosis. A high vorticity magnitude, especially in a bifurcation lesion, affects both the blood flow velocity and vorticity, promoting endothelial dysfunction and/or thrombogenicity. |
Stream function | Related to a change of the characteristic non-Newtonian fluid motion |
Strain rate | Low levels have been related to an in-stent restenosis |
Wall-shea> | High Wall-shear stress plays a major role in both generation, progression and destabilisation of atherosclerotic plaques |