Figure 6.

CAV1 Determines YAP Activation and ADM in Caerulein-Induced Acute Pancreatitis

(A) Immunohistochemistry analysis of YAP expression in pancreatic tissue of WT and Cav1KO mice 4 days after caerulein treatment.

(B) Quantification of the percentage of the nuclear area covered by YAP staining 2 hr and 4 days after caerulein treatment. n = 8.

(C) Quantification of the percentage pancreatic area showing extensive ADM after 4 days of chronic pancreatitis in WT mice (n = 4) and Cav1KO mice (n = 3).

Data in (B) and (C) are presented as means ± SEM; ^∗p < 0.05, ^∗∗p < 0.01. See also Figure S6.