Figure 4.
Comparison of the effects of EA on histological changes in wild-type mice and CB2−/− mice subjected to KOA induction.
Notes: (A) Representative histological knee joint sections (medial side) stained with Safranin O–Fast Green of wild-type mice and CB2−/− mice. Summary data show the effect of EA on the OARSI score of wild-type mice (B) and CB2−/− mice (C). Data are expressed as mean±SD (n=6 mice in each group). Scale bar: 100 µm. *P<0.05, compared with the control group; #P<0.05, compared with the KOA group.
Abbreviations: CON, control; EA, electroacupuncture; KOA, knee osteoarthritis; OARSI, Osteoarthritis Research Society International.